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The name itself emerged from popular culture references to Wolverine's superhuman healing abilities in X-Men comics and films

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However, the cellular ROS levels remained stable, and at higher concentrations of CB-839, only the HG-3 cell line demonstrated an increase in cellular ROS ( Figures 1F, H )

Mitochondrial swelling and loss of potential due to open mPTP is one of the signals for mitophagy to recognize damaged mitochondria [57]

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